The World Health Organization granted full regulatory approval to R21/Matrix-M, a malaria vaccine developed by the University of Oxford and manufactured by the Serum Institute of India. Phase 3 clinical trials confirmed 89% efficacy against clinical malaria in children under five — the highest efficacy ever achieved by any malaria vaccine.

Malaria kills approximately 600,000 people every year, the majority of them children under five in sub-Saharan Africa. The first WHO-approved malaria vaccine, RTS,S, offered just 36-40% protection.

Distribution Plans

Gavi, the Vaccine Alliance, has committed funding to procure 100 million doses annually at a negotiated price of $3.50 per dose, making the vaccine accessible to the lowest-income countries. Nigeria, the Democratic Republic of Congo and Ethiopia are expected to begin national vaccination campaigns within 18 months.